Quantifying the dynamics of the oligomeric transcription factor STAT3 by pair correlation of molecular brightness

Oligomerisation of transcription factors regulates their translocation into the nucleus, DNA binding affinity and sequence specificity. Here, Hinde et al. present a microscopy analysis, pair correlation of molecular brightness, that tracks the molecular mobility of different oligomeric species in th...

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Main Authors:	Elizabeth Hinde, Elvis Pandžić, Zhengmin Yang, Ivan H. W. Ng, David A. Jans, Marie A. Bogoyevitch, Enrico Gratton, Katharina Gaus
Format:	Article
Language:	English
Published:	Nature Publishing Group 2016-03-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/ncomms11047

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spelling	doaj-db96e5c3576b42e9b2eda1827f25dcda2021-05-11T10:48:22ZengNature Publishing GroupNature Communications2041-17232016-03-017111410.1038/ncomms11047Quantifying the dynamics of the oligomeric transcription factor STAT3 by pair correlation of molecular brightnessElizabeth Hinde0Elvis Pandžić1Zhengmin Yang2Ivan H. W. Ng3David A. Jans4Marie A. Bogoyevitch5Enrico Gratton6Katharina Gaus7EMBL Australia Node in Single Molecule Science, School of Medical Sciences, University of New South WalesEMBL Australia Node in Single Molecule Science, School of Medical Sciences, University of New South WalesEMBL Australia Node in Single Molecule Science, School of Medical Sciences, University of New South WalesProgram in Emerging Infectious Diseases, Duke-NUS Medical SchoolDepartment of Biochemistry and Molecular Biology, Nuclear Signalling Lab, Faculty of Biomedical and Psychological Sciences, Monash UniversityDepartment of Biochemistry and Molecular Biology, Cell Signalling Research Laboratories, University of MelbourneDepartment of Biomedical Engineering, Laboratory for Fluorescence Dynamics, University of CaliforniaEMBL Australia Node in Single Molecule Science, School of Medical Sciences, University of New South WalesOligomerisation of transcription factors regulates their translocation into the nucleus, DNA binding affinity and sequence specificity. Here, Hinde et al. present a microscopy analysis, pair correlation of molecular brightness, that tracks the molecular mobility of different oligomeric species in the same cell.https://doi.org/10.1038/ncomms11047
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Elizabeth Hinde Elvis Pandžić Zhengmin Yang Ivan H. W. Ng David A. Jans Marie A. Bogoyevitch Enrico Gratton Katharina Gaus
spellingShingle	Elizabeth Hinde Elvis Pandžić Zhengmin Yang Ivan H. W. Ng David A. Jans Marie A. Bogoyevitch Enrico Gratton Katharina Gaus Quantifying the dynamics of the oligomeric transcription factor STAT3 by pair correlation of molecular brightness Nature Communications
author_facet	Elizabeth Hinde Elvis Pandžić Zhengmin Yang Ivan H. W. Ng David A. Jans Marie A. Bogoyevitch Enrico Gratton Katharina Gaus
author_sort	Elizabeth Hinde
title	Quantifying the dynamics of the oligomeric transcription factor STAT3 by pair correlation of molecular brightness
title_short	Quantifying the dynamics of the oligomeric transcription factor STAT3 by pair correlation of molecular brightness
title_full	Quantifying the dynamics of the oligomeric transcription factor STAT3 by pair correlation of molecular brightness
title_fullStr	Quantifying the dynamics of the oligomeric transcription factor STAT3 by pair correlation of molecular brightness
title_full_unstemmed	Quantifying the dynamics of the oligomeric transcription factor STAT3 by pair correlation of molecular brightness
title_sort	quantifying the dynamics of the oligomeric transcription factor stat3 by pair correlation of molecular brightness
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2016-03-01
description	Oligomerisation of transcription factors regulates their translocation into the nucleus, DNA binding affinity and sequence specificity. Here, Hinde et al. present a microscopy analysis, pair correlation of molecular brightness, that tracks the molecular mobility of different oligomeric species in the same cell.
url	https://doi.org/10.1038/ncomms11047
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Quantifying the dynamics of the oligomeric transcription factor STAT3 by pair correlation of molecular brightness

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