Impact of valvular heart disease on hip replacement: a retrospective nationwide inpatient sample database study
Abstract Background To study the impact of valvular heart disease (VHD) on hip replacement, particularly the clinical impactions of aortic stenosis before total/partial hip arthroplasty. Methods This was a retrospective cohort study. Data on patients who had undergone hip replacement from 2005 to 20...
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doaj-dba0d7b9e68e49e7813cb093e15029d42021-10-10T11:36:10ZengBMCBMC Musculoskeletal Disorders1471-24742021-10-012211810.1186/s12891-021-04738-zImpact of valvular heart disease on hip replacement: a retrospective nationwide inpatient sample database studyQiang Lian0Jian Wang1Yun Lian2Qinfeng Yang3Mingchen Zhao4Yang Zhang5Division of Orthopaedic Surgery, Department of Orthopaedics, Nanfang Hospital, Southern Medical UniversityDivision of Orthopaedic Surgery, Department of Orthopaedics, Nanfang Hospital, Southern Medical UniversityFirst Affiliation Hospital of Nanchang UniversityDivision of Orthopaedic Surgery, Department of Orthopaedics, Nanfang Hospital, Southern Medical UniversityGoodwill Hessian Health Technology Co., Ltd.Division of Orthopaedic Surgery, Department of Orthopaedics, Nanfang Hospital, Southern Medical UniversityAbstract Background To study the impact of valvular heart disease (VHD) on hip replacement, particularly the clinical impactions of aortic stenosis before total/partial hip arthroplasty. Methods This was a retrospective cohort study. Data on patients who had undergone hip replacement from 2005 to 2014 were extracted from the NIS database. Independent t test and chi-square test were used to analyze the essential characteristics of patients. Multivariate regression was used to estimate the correlation among demographics, comorbidities, complications, hospitalization costs, and time. Results VHD accounted for 5.56% and AS accounted for 0.03% of the patients before hip replacement surgeries. Patients with VHD before hip replacement are related to the following characteristics: female patients (odds ratio [OR] = 1.15 [1.12–1.18]), elective admission (OR = 0.78 [0.76–0.80]), Charlson Comorbidity Index ≥3 (OR = 1.06 [1.03–1.08]), large-volume hospitals (OR = 1.13 [1.1–1.2]), teaching hospitals (OR = 5 4.4 [2.9–6.7]), and hospital location in urban areas (OR = 1.22 [1.2–1.3]). In addition, VHD is a risk factor for mortality and some acute postoperative medical complications, such as acute cardiac event (OR = 2.96 [2.87–3.04]), acute pulmonary edema (OR = 1.13 [1.06–1.21]), acute cerebrovascular event (OR = 1.22 [1.16–1.74]), and acute renal failure (OR = 1.22 [1.17–1.27]). It also has an impact on DVT/PE (OR = 0.89 [0.8–0.99]). Patients with AS before hip replacement have basic demographic characteristics like those of hip replacement patients with valvular disease. Patients with AS are older than those without AS before surgery (OR = 3.28 [2.27–4.75) and are related to the following characteristics: female patients (OR = 1.92 [1.32–2.8]) and elective admission (OR = 0.51 [0.36–0.75]). The perioperative period is limited to acute postoperative complications, such as acute cardiac events (OR = 2.50 [1.76–3.53]) and acute hepatic failure (OR = 7.69 [1.8–32.89]). Both valvular diseases and AS are associated with a higher mortality rate and hospitalization cost. Conclusion VHD independently predicted mortality rate and surgical and medical complications after total/partial hip arthroplasty.https://doi.org/10.1186/s12891-021-04738-zValvular heart diseaseHip replacementAortic stenosis |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Qiang Lian Jian Wang Yun Lian Qinfeng Yang Mingchen Zhao Yang Zhang |
spellingShingle |
Qiang Lian Jian Wang Yun Lian Qinfeng Yang Mingchen Zhao Yang Zhang Impact of valvular heart disease on hip replacement: a retrospective nationwide inpatient sample database study BMC Musculoskeletal Disorders Valvular heart disease Hip replacement Aortic stenosis |
author_facet |
Qiang Lian Jian Wang Yun Lian Qinfeng Yang Mingchen Zhao Yang Zhang |
author_sort |
Qiang Lian |
title |
Impact of valvular heart disease on hip replacement: a retrospective nationwide inpatient sample database study |
title_short |
Impact of valvular heart disease on hip replacement: a retrospective nationwide inpatient sample database study |
title_full |
Impact of valvular heart disease on hip replacement: a retrospective nationwide inpatient sample database study |
title_fullStr |
Impact of valvular heart disease on hip replacement: a retrospective nationwide inpatient sample database study |
title_full_unstemmed |
Impact of valvular heart disease on hip replacement: a retrospective nationwide inpatient sample database study |
title_sort |
impact of valvular heart disease on hip replacement: a retrospective nationwide inpatient sample database study |
publisher |
BMC |
series |
BMC Musculoskeletal Disorders |
issn |
1471-2474 |
publishDate |
2021-10-01 |
description |
Abstract Background To study the impact of valvular heart disease (VHD) on hip replacement, particularly the clinical impactions of aortic stenosis before total/partial hip arthroplasty. Methods This was a retrospective cohort study. Data on patients who had undergone hip replacement from 2005 to 2014 were extracted from the NIS database. Independent t test and chi-square test were used to analyze the essential characteristics of patients. Multivariate regression was used to estimate the correlation among demographics, comorbidities, complications, hospitalization costs, and time. Results VHD accounted for 5.56% and AS accounted for 0.03% of the patients before hip replacement surgeries. Patients with VHD before hip replacement are related to the following characteristics: female patients (odds ratio [OR] = 1.15 [1.12–1.18]), elective admission (OR = 0.78 [0.76–0.80]), Charlson Comorbidity Index ≥3 (OR = 1.06 [1.03–1.08]), large-volume hospitals (OR = 1.13 [1.1–1.2]), teaching hospitals (OR = 5 4.4 [2.9–6.7]), and hospital location in urban areas (OR = 1.22 [1.2–1.3]). In addition, VHD is a risk factor for mortality and some acute postoperative medical complications, such as acute cardiac event (OR = 2.96 [2.87–3.04]), acute pulmonary edema (OR = 1.13 [1.06–1.21]), acute cerebrovascular event (OR = 1.22 [1.16–1.74]), and acute renal failure (OR = 1.22 [1.17–1.27]). It also has an impact on DVT/PE (OR = 0.89 [0.8–0.99]). Patients with AS before hip replacement have basic demographic characteristics like those of hip replacement patients with valvular disease. Patients with AS are older than those without AS before surgery (OR = 3.28 [2.27–4.75) and are related to the following characteristics: female patients (OR = 1.92 [1.32–2.8]) and elective admission (OR = 0.51 [0.36–0.75]). The perioperative period is limited to acute postoperative complications, such as acute cardiac events (OR = 2.50 [1.76–3.53]) and acute hepatic failure (OR = 7.69 [1.8–32.89]). Both valvular diseases and AS are associated with a higher mortality rate and hospitalization cost. Conclusion VHD independently predicted mortality rate and surgical and medical complications after total/partial hip arthroplasty. |
topic |
Valvular heart disease Hip replacement Aortic stenosis |
url |
https://doi.org/10.1186/s12891-021-04738-z |
work_keys_str_mv |
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