Cardiac morbidity in HIV infection is associated with checkpoint inhibitor LAG-3 on CD4 T cells.

Cardiac morbidity in HIV infection is associated with checkpoint inhibitor LAG-3 on CD4 T cells.

Recent findings point to a role of Checkpoint Inhibitor (CPI) receptors at the tissue level in immune homeostasis. Here we investigated the role of CPI molecules on immune cells in relation to cardiac function. Participants recruited in Chennai, India consisted of HIV+ ART naive viremic (Gp1 n = 102...

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Bibliographic Details
Main Authors: Suresh Pallikkuth, Rajendra Pahwa, Bagavathi Kausalya, Shanmugam Saravanan, Li Pan, R Vignesh, Syed Iqbal, Sunil S Solomon, Kailapuri G Murugavel, Selvamuthu Poongulali, Nagalingeswaran Kumarasamy, Savita Pahwa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6209232?pdf=render

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http://europepmc.org/articles/PMC6209232?pdf=render

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