Detection of a soluble form of CD109 in serum of CD109 transgenic and tumor xenografted mice.

Detection of a soluble form of CD109 in serum of CD109 transgenic and tumor xenografted mice.

CD109, a glycosylphosphatidylinositol-anchored glycoprotein, is expressed at high levels in some human tumors including squamous cell carcinomas. As CD109 is reportedly cleaved by furin and its soluble form is secreted into culture medium in vitro, we hypothesized that CD109 could serve as a tumor m...

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Main Authors: Hiroki Sakakura, Yoshiki Murakumo, Shinji Mii, Sumitaka Hagiwara, Takuya Kato, Masato Asai, Akiyoshi Hoshino, Noriyuki Yamamoto, Sayaka Sobue, Masatoshi Ichihara, Minoru Ueda, Masahide Takahashi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3882221?pdf=render

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