Sirolimus-Eluting Electrospun-Produced Matrices as Coatings for Vascular Stents: Dependence of Drug Release on Matrix Structure and Composition of the External Environment

Sirolimus-Eluting Electrospun-Produced Matrices as Coatings for Vascular Stents: Dependence of Drug Release on Matrix Structure and Composition of the External Environment

Although a number of drug-eluting coatings for vascular stents (VSs) have been developed and are in commercial use, more efficient stent coatings and drug delivery systems are needed. Sirolimus (SRL) is a clinically important drug with antiproliferative and immunosuppressive activities that is widel...

Full description

Bibliographic Details
Main Authors: Zhanna K. Nazarkina, Boris P. Chelobanov, Vera S. Chernonosova, Irina V. Romanova, Andrey A. Karpenko, Pavel P. Laktionov
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Materials
Subjects:
sirolimus
electrospinning
drug release
polycaprolactone
3D matrix
drug-eluting stents
Online Access:https://www.mdpi.com/1996-1944/13/12/2692

Similar Items

Similar Items