The kinase LRRK2 is differently expressed in chronic rhinosinusitis with and without nasal polyps

The kinase LRRK2 is differently expressed in chronic rhinosinusitis with and without nasal polyps

Abstract Background Chronic rhinosinusitis (CRS), commonly divided into CRS with nasal polyps (CRSwNP) and without nasal polyps (CRSsNP) is an inflammatory disease which mechanism remain unclear. Leucine-rich repeat kinase 2 (LRRK2) has been proved to be a negative regulator of inflammation response...

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Bibliographic Details
Main Authors: Yue Ma, Chunquan Zheng, Le Shi
Format: Article
Language:English
Published: Wiley 2018-03-01
Series:Clinical and Translational Allergy
Subjects:
LRRK2
NRON
Long non-coding RNA
Chronic rhinosinusitis
Pro-inflammatory cytokine
Online Access:http://link.springer.com/article/10.1186/s13601-018-0194-y

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