Optical characteristics after Descemet membrane endothelial keratoplasty: 1-year results.
<h4>Purpose</h4>To evaluate the corneal characteristics after Descemet membrane endothelial keratoplasty (DMEK) compared with normal corneas.<h4>Methods</h4>Patients who underwent DMEK at Yokohama Minami Kyosai Hospital were included and prospectively evaluated pre-operativel...
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doaj-dbcf935d81b9478391ea1842f634b6dd2021-03-04T11:10:30ZengPublic Library of Science (PLoS)PLoS ONE1932-62032020-01-011510e024045810.1371/journal.pone.0240458Optical characteristics after Descemet membrane endothelial keratoplasty: 1-year results.Takahiko HayashiAkira KobayashiHidenori TakahashiItaru OyakawaNaoko KatoTakefumi Yamaguchi<h4>Purpose</h4>To evaluate the corneal characteristics after Descemet membrane endothelial keratoplasty (DMEK) compared with normal corneas.<h4>Methods</h4>Patients who underwent DMEK at Yokohama Minami Kyosai Hospital were included and prospectively evaluated pre-operatively and at postoperative months 1, 3, 6, and 12, and compared to healthy controls. Corneal characteristics evaluated included corneal curvature (keratometric value [KV]; D), central corneal thickness (CCT), peripheral corneal thickness (PCT), and corneal higher-order aberrations [HOAs] at 6.0 mm diameter, calculated by anterior segment optical coherence tomography and logarithm of the minimal angle of resolution [logMAR].<h4>Results</h4>A total of 30 eyes of 30 patients (6 men, 24 women, mean age 73.4 ± 7.4 years) were included and compared with 31 age-matched healthy control eyes (13 men, 18 women; mean age 73.0 ± 6.7 years). LogMAR after DMEK improved from 0.87 ± 0.07 preoperatively to 0.04 ± 0.07 at 12 months postoperatively (p<0.001). Although anterior KVs of DMEK eyes were similar to those of control eyes, posterior KVs were significantly larger (-6.4 ± 0.3 D vs. -6.3 ± 0.2 D; p = 0.02). Total HOAs after DMEK improved from 1.94 ± 1.05 μm preoperatively to 1.05 ± 0.16 μm at 12 months postoperatively (p<0.001), which was significantly higher than that in control eyes (0.63 ± 0.06) (p<0.001). Despite the similar CCTs in the two groups, the PCT was significantly larger in DMEK eyes (704 ± 41 μm vs 669 ± 38 μm, p = 0.002) at 12 months.<h4>Conclusion</h4>Despite achieving good visual function and excellent corneal clarity, eyes that underwent DMEK showed a steeper posterior KV and higher corneal HOAs than normal eyes even at 12 months after surgery.https://doi.org/10.1371/journal.pone.0240458 |
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DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Takahiko Hayashi Akira Kobayashi Hidenori Takahashi Itaru Oyakawa Naoko Kato Takefumi Yamaguchi |
spellingShingle |
Takahiko Hayashi Akira Kobayashi Hidenori Takahashi Itaru Oyakawa Naoko Kato Takefumi Yamaguchi Optical characteristics after Descemet membrane endothelial keratoplasty: 1-year results. PLoS ONE |
author_facet |
Takahiko Hayashi Akira Kobayashi Hidenori Takahashi Itaru Oyakawa Naoko Kato Takefumi Yamaguchi |
author_sort |
Takahiko Hayashi |
title |
Optical characteristics after Descemet membrane endothelial keratoplasty: 1-year results. |
title_short |
Optical characteristics after Descemet membrane endothelial keratoplasty: 1-year results. |
title_full |
Optical characteristics after Descemet membrane endothelial keratoplasty: 1-year results. |
title_fullStr |
Optical characteristics after Descemet membrane endothelial keratoplasty: 1-year results. |
title_full_unstemmed |
Optical characteristics after Descemet membrane endothelial keratoplasty: 1-year results. |
title_sort |
optical characteristics after descemet membrane endothelial keratoplasty: 1-year results. |
publisher |
Public Library of Science (PLoS) |
series |
PLoS ONE |
issn |
1932-6203 |
publishDate |
2020-01-01 |
description |
<h4>Purpose</h4>To evaluate the corneal characteristics after Descemet membrane endothelial keratoplasty (DMEK) compared with normal corneas.<h4>Methods</h4>Patients who underwent DMEK at Yokohama Minami Kyosai Hospital were included and prospectively evaluated pre-operatively and at postoperative months 1, 3, 6, and 12, and compared to healthy controls. Corneal characteristics evaluated included corneal curvature (keratometric value [KV]; D), central corneal thickness (CCT), peripheral corneal thickness (PCT), and corneal higher-order aberrations [HOAs] at 6.0 mm diameter, calculated by anterior segment optical coherence tomography and logarithm of the minimal angle of resolution [logMAR].<h4>Results</h4>A total of 30 eyes of 30 patients (6 men, 24 women, mean age 73.4 ± 7.4 years) were included and compared with 31 age-matched healthy control eyes (13 men, 18 women; mean age 73.0 ± 6.7 years). LogMAR after DMEK improved from 0.87 ± 0.07 preoperatively to 0.04 ± 0.07 at 12 months postoperatively (p<0.001). Although anterior KVs of DMEK eyes were similar to those of control eyes, posterior KVs were significantly larger (-6.4 ± 0.3 D vs. -6.3 ± 0.2 D; p = 0.02). Total HOAs after DMEK improved from 1.94 ± 1.05 μm preoperatively to 1.05 ± 0.16 μm at 12 months postoperatively (p<0.001), which was significantly higher than that in control eyes (0.63 ± 0.06) (p<0.001). Despite the similar CCTs in the two groups, the PCT was significantly larger in DMEK eyes (704 ± 41 μm vs 669 ± 38 μm, p = 0.002) at 12 months.<h4>Conclusion</h4>Despite achieving good visual function and excellent corneal clarity, eyes that underwent DMEK showed a steeper posterior KV and higher corneal HOAs than normal eyes even at 12 months after surgery. |
url |
https://doi.org/10.1371/journal.pone.0240458 |
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