The Antileishmanial Potential of C-3 Functionalized Isobenzofuranones against Leishmania (Leishmania) Infantum Chagasi

The Antileishmanial Potential of C-3 Functionalized Isobenzofuranones against Leishmania (Leishmania) Infantum Chagasi

Leishmaniases are diseases caused by protozoan parasites of the genus Leishmania. Clinically, leishmaniases range from cutaneous to visceral forms, with estimated global incidences of 1.2 and 0.4 million cases per year, respectively. The treatment of these diseases relies on multiple parenteral inje...

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Bibliographic Details
Main Authors: Wagner Luiz Pereira, Raphael de Souza Vasconcellos, Christiane Mariotini-Moura, Rodrigo Saar Gomes, Rafaela de Cássia Firmino, Adalberto Manoel da Silva, Abelardo Silva Júnior, Gustavo Costa Bressan, Márcia Rogéria Almeida, Luís Carlos Crocco Afonso, Róbson Ricardo Teixeira, Juliana Lopes Rangel Fietto
Format: Article
Language:English
Published: MDPI AG 2015-12-01
Series:Molecules
Subjects:
Leishmania (L.) infantum chagasi
visceral leishmaniasis
isobenzofuranones
phthalides
in vitro leishmanicidal activity
Online Access:http://www.mdpi.com/1420-3049/20/12/19857

Internet

http://www.mdpi.com/1420-3049/20/12/19857

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