Nr2e1 ablation impairs liver glucolipid metabolism and induces inflammation, high-fat diets amplify the damage

Nr2e1 ablation impairs liver glucolipid metabolism and induces inflammation, high-fat diets amplify the damage

Nonalcoholic fatty liver disease (NAFLD) is a common and complex metabolic disorder. Despite the widespread concern, there are still few effective treatments except lifestyle interventions. Nuclear receptor subfamily 2 group E member 1 (Nr2e1) is a transcription factor which regulates many biologica...

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Bibliographic Details
Main Authors: Qing Xiong, Yuwen Wu, Miao Yang, Guijun Wu, Ye Wang, Huawei Wang, Jieyuan Feng, Linyang Song, Beier Tong, Guangzhen He, Yancheng Xu
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Nr2e1
Nonalcoholic fatty liver disease
Insulin resistance
Lipid metabolism
Inflammation
High fat diet
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332219335620

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