Fever of unknown origin as the major manifestation of subacute thyroiditis

• Main Authors: Ahmad Housin, Marc P Pusztaszeri, Michael Tamilia
• Format: Article
• Language: English
• Published: Bioscientifica 2021-03-01
• Series: Endocrinology, Diabetes & Metabolism Case Reports
• Online Access: https://edm.bioscientifica.com/view/journals/edm/2021/1/EDM20-0179.xml

Fever of unknown origin is a commonly encountered medical problem. Most common causes include infections, malignancy, and connective tissue diseases. Endocrine causes are rare but are well documented. While fever is common in some endocrine disorders, fever of unknown origin as the sole presenting feature is very rare. We describe a case report of a 63-year-old male who presents with fever of unknown origin. Imaging and biopsy results confirmed the diagnosis of subacute thyroiditis. He was started on prednisone with a good response. We conclude that subacute thyroiditis should be considered in the work up of fever of unknown origin even in the absence of classical signs and symptoms.