Genome Plasticity in Cultured Leishmania donovani: Comparison of Early and Late Passages

Genome Plasticity in Cultured Leishmania donovani: Comparison of Early and Late Passages

Leishmania donovani possesses a complex heteroxenic life cycle where infective metacyclic promastigotes are pre-adapted to infect their host and cope up with intracellular stress. Exploiting the similarities between cultured and sandfly derived promastigotes, we used early and late passage cultured...

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Bibliographic Details
Main Authors: Roma Sinha, Mathu Malar C, Raghwan, Subhadeep Das, Sonali Das, Mohammad Shadab, Rukhsana Chowdhury, Sucheta Tripathy, Nahid Ali
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Microbiology
Subjects:
Leishmania donovani
genomics
in vitro passage
promastigotes
genome plasticity
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.01279/full

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