Increased microparticle production and impaired microvascular endothelial function in aldosterone-salt-treated rats: protective effects of polyphenols.

Increased microparticle production and impaired microvascular endothelial function in aldosterone-salt-treated rats: protective effects of polyphenols.

We aimed to characterize circulating microparticles in association with arterial stiffness, inflammation and endothelial dysfunction in aldosterone-salt-induced hypertension in rats and to investigate the preventive effects of red wine polyphenols. Uninephrectomized male Sprague-Dawley rats were tre...

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Bibliographic Details
Main Authors: Natalia López Andrés, Angela Tesse, Véronique Regnault, Huguette Louis, Valérie Cattan, Simon N Thornton, Carlos Labat, Agustine Kakou, Simon Tual-Chalot, Sébastien Faure, Pascale Challande, Mary Osborne-Pellegrin, M Carmen Martínez, Patrick Lacolley, Ramaroson Andriantsitohaina
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3393732?pdf=render

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