In vitro activity of thienyl-2-nitropropene compounds against Trypanosoma cruzi

In vitro activity of thienyl-2-nitropropene compounds against Trypanosoma cruzi

The in vitro activity of four 2-nitropropene derivatives, 1-(3-benzothienyl)-2-nitropropene (N1), 1-(3-thienyl)-2-nitropropene (N2), 1-(5-bromo-2-thienyl)-2-nitropropene (N3) and 1-(4-bromo-2-thienyl)-2-nitropropene (N4), were tested against cultures of the parasite Trypanosoma cruzi. Cytotoxicity s...

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Bibliographic Details
Main Authors:	Cristina Herrera, Gabriel A Vallejos, Randall Loaiza, Rodrigo Zeledón, Andrea Urbina, Silvia Sepúlveda-Boza
Format:	Article
Language:	English
Published:	Instituto Oswaldo Cruz, Ministério da Saúde 2009-11-01
Series:	Memórias do Instituto Oswaldo Cruz.
Subjects:	Trypanosoma cruzi thienyl-2-nitropropene compounds Chagas disease antitrypanosomal activity
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762009000700007

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