Quantitative Angiographic Assessment of Aortic Regurgitation after Transcatheter Aortic Valve Implantation among Three Balloon-Expandable Valves
Objectives: The aim of the present analysis is to compare the quantitative angiographic aortic regurgitation (AR) after transcatheter aortic valve implantation (TAVI) among three balloon-expandable valves. Background: Quantitative videodensitometric aortography is an objective, accurate, and reprodu...
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doaj-dc2968f2b08d443f87e853eede8be8e42021-04-27T07:15:16ZengUbiquity PressGlobal Heart2211-81792021-03-0116110.5334/gh.959831Quantitative Angiographic Assessment of Aortic Regurgitation after Transcatheter Aortic Valve Implantation among Three Balloon-Expandable ValvesHideyuki Kawashima0Rutao Wang1Darren Mylotte2Dariusz Jagielak3Frederico De Marco4Alfonso Ielasi5Yoshinobu Onuma6Peter den Heijer7Christian Juhl Terkelsen8William Wijns9Patrick W. Serruys10Osama Soliman11Department of Cardiology, National University of Ireland, Galway (NUIG), Galway, Ireland and CORRIB Corelab and Center for Research and Imaging, IE; Amsterdam UMC, University of Amsterdam, AmsterdamDepartment of Cardiology, National University of Ireland, Galway (NUIG), Galway, Ireland and CORRIB Corelab and Center for Research and Imaging, IE; Department of Cardiology, Radboud University Medical Center, NijmegenDepartment of Cardiology, National University of Ireland, Galway (NUIG), Galway, Ireland and CORRIB Corelab and Center for Research and ImagingDepartment of Cardiac and Vascular Surgery, Medical University of Gdansk, GdanskClinical and Interventional Cardiology Department, IRCCS Policlinico San Donato, San Donato MilaneseInterventional Cardiology Unit, Istituto Clinico Sant’Ambrogio, MilanDepartment of Cardiology, National University of Ireland, Galway (NUIG), Galway, Ireland and CORRIB Corelab and Center for Research and ImagingDepartment of Cardiology, Amphia Ziekenhuis, BredaDepartment of Cardiology, Aarhus University Hospital, AarhusDepartment of Cardiology, National University of Ireland, Galway (NUIG), Galway, Ireland and CORRIB Corelab and Center for Research and ImagingDepartment of Cardiology, National University of Ireland, Galway (NUIG), Galway, Ireland and CORRIB Corelab and Center for Research and Imaging; NHLI, Imperial College London, LondonDepartment of Cardiology, National University of Ireland, Galway (NUIG), Galway, Ireland and CORRIB Corelab and Center for Research and ImagingObjectives: The aim of the present analysis is to compare the quantitative angiographic aortic regurgitation (AR) after transcatheter aortic valve implantation (TAVI) among three balloon-expandable valves. Background: Quantitative videodensitometric aortography is an objective, accurate, and reproducible tool for adjudication of AR following TAVI. Methods: This is a retrospective corelab analysis, independent from industry, of aortograms from patients treated with TAVI using the balloon-expandable Myval transcatheter heart valve (THV) (Meril Life Sciences Pvt. Ltd., India), Sapien 3, and XT THVs (Edwards Lifesciences, Irvine, CA, USA). The study comprised of 108 analyzable aortograms from consecutive patients in a multicenter European registry who underwent Myval THV implantation. The results of quantitative assessment of AR in the Sapien 3 THV (n = 397) and Sapien XT THV (n = 239) were retrieved from a published pooled database. Results: The Myval THV had the lowest proportion of patients with moderate or severe angiographic quantitative AR (2.8%) compared to the Sapien 3 THV (8.3%; p = 0.049) and Sapien XT THV (10.9%; p = 0.012). Furthermore, the Myval THV had the lowest mean angiographic quantitative AR (6.3 ± 6.3%), followed by Sapien 3 THV (7.6 ± 7.1%) and Sapien XT THV (8.8 ± 7.5%), and it was significantly lower than that of the Sapien XT THV (p = 0.006), but not significantly different from Sapien 3 THV (p = 0.246). Conclusion: The Myval THV, in comparison with other BEV’s analyzed in our database, showed a lower occurrence of moderate or severe AR after TAVI. These results should be confirmed in prospective cohorts of randomized patients with head-to-head THV comparisons.https://globalheartjournal.com/articles/959aortic stenosisballoon-expandable valveparavalvular regurgitationtranscatheter aortic valve implantationtranscatheter heart valve |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Hideyuki Kawashima Rutao Wang Darren Mylotte Dariusz Jagielak Frederico De Marco Alfonso Ielasi Yoshinobu Onuma Peter den Heijer Christian Juhl Terkelsen William Wijns Patrick W. Serruys Osama Soliman |
spellingShingle |
Hideyuki Kawashima Rutao Wang Darren Mylotte Dariusz Jagielak Frederico De Marco Alfonso Ielasi Yoshinobu Onuma Peter den Heijer Christian Juhl Terkelsen William Wijns Patrick W. Serruys Osama Soliman Quantitative Angiographic Assessment of Aortic Regurgitation after Transcatheter Aortic Valve Implantation among Three Balloon-Expandable Valves Global Heart aortic stenosis balloon-expandable valve paravalvular regurgitation transcatheter aortic valve implantation transcatheter heart valve |
author_facet |
Hideyuki Kawashima Rutao Wang Darren Mylotte Dariusz Jagielak Frederico De Marco Alfonso Ielasi Yoshinobu Onuma Peter den Heijer Christian Juhl Terkelsen William Wijns Patrick W. Serruys Osama Soliman |
author_sort |
Hideyuki Kawashima |
title |
Quantitative Angiographic Assessment of Aortic Regurgitation after Transcatheter Aortic Valve Implantation among Three Balloon-Expandable Valves |
title_short |
Quantitative Angiographic Assessment of Aortic Regurgitation after Transcatheter Aortic Valve Implantation among Three Balloon-Expandable Valves |
title_full |
Quantitative Angiographic Assessment of Aortic Regurgitation after Transcatheter Aortic Valve Implantation among Three Balloon-Expandable Valves |
title_fullStr |
Quantitative Angiographic Assessment of Aortic Regurgitation after Transcatheter Aortic Valve Implantation among Three Balloon-Expandable Valves |
title_full_unstemmed |
Quantitative Angiographic Assessment of Aortic Regurgitation after Transcatheter Aortic Valve Implantation among Three Balloon-Expandable Valves |
title_sort |
quantitative angiographic assessment of aortic regurgitation after transcatheter aortic valve implantation among three balloon-expandable valves |
publisher |
Ubiquity Press |
series |
Global Heart |
issn |
2211-8179 |
publishDate |
2021-03-01 |
description |
Objectives: The aim of the present analysis is to compare the quantitative angiographic aortic regurgitation (AR) after transcatheter aortic valve implantation (TAVI) among three balloon-expandable valves. Background: Quantitative videodensitometric aortography is an objective, accurate, and reproducible tool for adjudication of AR following TAVI. Methods: This is a retrospective corelab analysis, independent from industry, of aortograms from patients treated with TAVI using the balloon-expandable Myval transcatheter heart valve (THV) (Meril Life Sciences Pvt. Ltd., India), Sapien 3, and XT THVs (Edwards Lifesciences, Irvine, CA, USA). The study comprised of 108 analyzable aortograms from consecutive patients in a multicenter European registry who underwent Myval THV implantation. The results of quantitative assessment of AR in the Sapien 3 THV (n = 397) and Sapien XT THV (n = 239) were retrieved from a published pooled database. Results: The Myval THV had the lowest proportion of patients with moderate or severe angiographic quantitative AR (2.8%) compared to the Sapien 3 THV (8.3%; p = 0.049) and Sapien XT THV (10.9%; p = 0.012). Furthermore, the Myval THV had the lowest mean angiographic quantitative AR (6.3 ± 6.3%), followed by Sapien 3 THV (7.6 ± 7.1%) and Sapien XT THV (8.8 ± 7.5%), and it was significantly lower than that of the Sapien XT THV (p = 0.006), but not significantly different from Sapien 3 THV (p = 0.246). Conclusion: The Myval THV, in comparison with other BEV’s analyzed in our database, showed a lower occurrence of moderate or severe AR after TAVI. These results should be confirmed in prospective cohorts of randomized patients with head-to-head THV comparisons. |
topic |
aortic stenosis balloon-expandable valve paravalvular regurgitation transcatheter aortic valve implantation transcatheter heart valve |
url |
https://globalheartjournal.com/articles/959 |
work_keys_str_mv |
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