Myelin activates FAK/Akt/NF-kappaB pathways and provokes CR3-dependent inflammatory response in murine system.

Myelin activates FAK/Akt/NF-kappaB pathways and provokes CR3-dependent inflammatory response in murine system.

Inflammatory response following central nervous system (CNS) injury contributes to progressive neuropathology and reduction in functional recovery. Axons are sensitive to mechanical injury and toxic inflammatory mediators, which may lead to demyelination. Although it is well documented that degenera...

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Bibliographic Details
Main Authors: Xin Sun, Xi Wang, Tianxiang Chen, Tianyi Li, Kai Cao, Andrew Lu, Yongxiong Chen, Dongming Sun, Jianhong Luo, Jianqing Fan, Wise Young, Yi Ren
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-02-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2826415?pdf=render

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http://europepmc.org/articles/PMC2826415?pdf=render

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