Ionic Liquid as an Efficient Medium for the Synthesis of Quinoline Derivatives via α-Chymotrypsin-Catalyzed Friedländer Condensation

Ionic Liquid as an Efficient Medium for the Synthesis of Quinoline Derivatives via α-Chymotrypsin-Catalyzed Friedländer Condensation

An efficient, convenient, and eco-friendly biocatalytic approach was developed for the synthesis of quinoline derivatives via the α-chymotrypsin-catalyzed Friedländer reaction. Interestingly, α-chymotrypsin exhibited higher catalytic activity in an ionic liquid (IL) aqueous solution as compared to t...

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Bibliographic Details
Main Authors:	Zhang-Gao Le, Meng Liang, Zhong-Sheng Chen, Sui-Hong Zhang, Zong-Bo Xie
Format:	Article
Language:	English
Published:	MDPI AG 2017-05-01
Series:	Molecules
Subjects:	Friedländer reaction quinolines α-chymotrypsin ionic liquid biocatalysis promiscuity
Online Access:	http://www.mdpi.com/1420-3049/22/5/762

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