X-radiation inhibits histone deacetylase 1 and 2, upregulates Axin expression and induces apoptosis in non-small cell lung cancer

X-radiation inhibits histone deacetylase 1 and 2, upregulates Axin expression and induces apoptosis in non-small cell lung cancer

<p>Abstract</p> <p>Background</p> <p>Histone deacetylase (HDAC) plays an important role in the deacetylation of histone, which can alter gene expression patterns and affect cell behavior associated with malignant transformation. The aims of this study were to investigat...

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Bibliographic Details
Main Authors: Han Yang, Zhang Yong, Yang Lian-he, Mi Xiao-yi, Dai Shun-dong, Li Qing-chang, Xu Hong-tao, Yu Juan-han, Li Guang, Zhao Jing, Han Chong, Yuan Xi-ming, Wang En-hua
Format: Article
Language:English
Published: BMC 2012-10-01
Series:Radiation Oncology
Subjects:
HDAC1
HDAC2
Axin
Lung neoplasm
Radiosensitization
Online Access:http://www.ro-journal.com/content/7/1/183

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