Natriuretic peptides and their usefulness in clinical practise

• Main Authors: Aleksandra Skałecka, Karol Krupa, Aleksandra Słabczyńska, Małgorzata Romaniuk, Konrad Suswał, Janusz Milanowski
• Format: Article
• Language: English
• Published: Kazimierz Wielki University 2020-09-01
• Series: Journal of Education, Health and Sport
• Subjects: natriuretic peptide; atrial natriuretic peptide; brain natriuretic peptide; heart failure; hypertrophic cardiomyopathy
• Online Access: https://apcz.umk.pl/czasopisma/index.php/JEHS/article/view/31245

<div class="OutlineElement Ltr BCX0 SCXW183210463"><p class="Paragraph SCXW183210463 BCX0"><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">Natriuretic</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="NormalTextRun SCXW183210463 BCX0"> </span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">peptides</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="NormalTextRun SCXW183210463 BCX0"> </span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">are</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="NormalTextRun SCXW183210463 BCX0"> </span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">peptic</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="NormalTextRun SCXW183210463 BCX0"> </span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">hormones</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="NormalTextRun SCXW183210463 BCX0"> </span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">produced</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"> by </span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">atrial</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"> and </span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">ventricular</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="NormalTextRun SCXW183210463 BCX0"> </span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">myocytes</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto">, and by </span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">endothelium</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"> of </span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">blood</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="NormalTextRun SCXW183210463 BCX0"> </span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">vessels</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto">, </span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">that</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="NormalTextRun SCXW183210463 BCX0"> </span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">take</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"> part in </span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">homeostatic</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="NormalTextRun SCXW183210463 BCX0"> </span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">control</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"> of </span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">water</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"> and </span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">sodium</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="NormalTextRun SCXW183210463 BCX0"> </span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">levels</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto">, but </span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">also</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="NormalTextRun SCXW183210463 BCX0"> </span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">potassium</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"> transport, </span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">lipolysis</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"> in </span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">adipocytes</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"> and </span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">blood</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="NormalTextRun SCXW183210463 BCX0"> </span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">pressure</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="NormalTextRun SCXW183210463 BCX0"> </span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">regulation</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto">. </span><span class="EOP SCXW183210463 BCX0" data-ccp-props="{&quot;201341983&quot;:0,&quot;335559738&quot;:40,&quot;335559739&quot;:40,&quot;335559740&quot;:276}"> </span></p></div><div class="OutlineElement Ltr BCX0 SCXW183210463"><p class="Paragraph SCXW183210463 BCX0"><span class="EOP SCXW183210463 BCX0" data-ccp-props="{&quot;201341983&quot;:0,&quot;335559738&quot;:40,&quot;335559739&quot;:40,&quot;335559740&quot;:276}"> </span></p></div><div class="OutlineElement Ltr BCX0 SCXW183210463"><p class="Paragraph SCXW183210463 BCX0"><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto">Three </span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">different</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="NormalTextRun SCXW183210463 BCX0"> </span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">natriuretic</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="NormalTextRun SCXW183210463 BCX0"> </span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">peptides</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="NormalTextRun SCXW183210463 BCX0"> </span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">are</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="NormalTextRun SCXW183210463 BCX0"> </span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">distinguished</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto">: </span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">atrial</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="NormalTextRun SCXW183210463 BCX0"> </span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">natriuretic</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="NormalTextRun SCXW183210463 BCX0"> </span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">peptide</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"> (ANP), b-</span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">type</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="NormalTextRun SCXW183210463 BCX0"> </span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">natriuretic</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="NormalTextRun SCXW183210463 BCX0"> </span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">peptide</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"> (BNP) and c-</span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">type</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="NormalTextRun SCXW183210463 BCX0"> </span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">natriuretic</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="NormalTextRun SCXW183210463 BCX0"> </span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">peptide</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"> (CNP). </span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">Those</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="NormalTextRun SCXW183210463 BCX0"> </span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">peptides</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="NormalTextRun SCXW183210463 BCX0"> </span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">are</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="NormalTextRun SCXW183210463 BCX0"> </span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">responsible</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="NormalTextRun SCXW183210463 BCX0"> </span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">mostly</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"> for </span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">water-sodium</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="NormalTextRun SCXW183210463 BCX0"> </span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">homeostasis</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"> and </span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">regulation</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"> of </span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">blood</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="NormalTextRun SCXW183210463 BCX0"> </span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">pressure</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto">. </span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">Levels</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"> of </span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">natriuretic</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="NormalTextRun SCXW183210463 BCX0"> </span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">peptides</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="NormalTextRun SCXW183210463 BCX0"> </span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">increase</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="NormalTextRun SCXW183210463 BCX0"> </span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">significantly</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"> in </span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">diseases</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"> and </span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">disorders</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="NormalTextRun SCXW183210463 BCX0"> </span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">such</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"> as </span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">congestive</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="NormalTextRun SCXW183210463 BCX0"> </span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">heart</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="NormalTextRun SCXW183210463 BCX0"> </span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">failure</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"> and </span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">pulmonary</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="NormalTextRun SCXW183210463 BCX0"> </span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">hypertension</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto">, </span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">that</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="NormalTextRun SCXW183210463 BCX0"> </span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">is</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="NormalTextRun SCXW183210463 BCX0"> </span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">why</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="NormalTextRun SCXW183210463 BCX0"> </span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">natriuretic</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="NormalTextRun SCXW183210463 BCX0"> </span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">peptides</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="NormalTextRun SCXW183210463 BCX0"> </span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">were</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="NormalTextRun SCXW183210463 BCX0"> </span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">found</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="NormalTextRun SCXW183210463 BCX0"> </span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">useful</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"> in </span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">diagnosis</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"> and monitoring of </span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">said</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="NormalTextRun SCXW183210463 BCX0"> </span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">diseases</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto">. In </span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">clinical</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="NormalTextRun SCXW183210463 BCX0"> </span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">practise</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto">, BNP and NT-</span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">proBNP</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="NormalTextRun SCXW183210463 BCX0"> </span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">levels</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="NormalTextRun SCXW183210463 BCX0"> </span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">are</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="NormalTextRun SCXW183210463 BCX0"> </span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">mostly</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="NormalTextRun SCXW183210463 BCX0"> </span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto"><span class="SpellingError SCXW183210463 BCX0">used</span></span><span class="TextRun SCXW183210463 BCX0" lang="PL" xml:lang="PL" data-contrast="auto">. </span><span class="EOP SCXW183210463 BCX0" data-ccp-props="{&quot;201341983&quot;:0,&quot;335559738&quot;:40,&quot;335559739&quot;:40,&quot;335559740&quot;:276}"> </span></p></div><div class="OutlineElement Ltr SCXW183210463 BCX0"><p class="Paragraph SCXW183210463 BCX0"><span class="EOP SCXW183210463 BCX0" data-ccp-props="{&quot;201341983&quot;:0,&quot;335559740&quot;:276}"> </span></p></div>