Alzheimer's disease - etiology and pathogenesis

Alzheimer's disease (AD) is one of the neurodegenerative diseases of the senile age that is most prevalent in the modern world. With regard to the population of people aged 60 years, the incidence of Alzheimer's disease is estimated at 1%, while in the population of people aged 90 and over...

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Main Authors: Grzegorz Wróbel, Paweł Zieliński, Jakub Spałek
Format: Article
Language:English
Published: Kazimierz Wielki University 2017-12-01
Series:Journal of Education, Health and Sport
Subjects:
Online Access:http://www.ojs.ukw.edu.pl/index.php/johs/article/view/5198
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spelling doaj-dc8d29458cf542418f992de3f4ab9d072020-11-25T01:35:04ZengKazimierz Wielki UniversityJournal of Education, Health and Sport2391-83062017-12-0171234935510.5281/zenodo.11393124850Alzheimer's disease - etiology and pathogenesisGrzegorz Wróbel0Paweł Zieliński1Jakub Spałek2Department of Human Anatomy, Faculty of Medicine and Health Sciences, Jan Kochanowski University, Al. IX Wieków Kielc 19 A 25-317 Kielce, Poland;Department of Human Anatomy, Faculty of Medicine and Health Sciences, Jan Kochanowski University, Al. IX Wieków Kielc 19 A 25-317 Kielce, Poland;Department of Human Anatomy, Faculty of Medicine and Health Sciences, Jan Kochanowski University, Al. IX Wieków Kielc 19 A 25-317 Kielce, Poland;Alzheimer's disease (AD) is one of the neurodegenerative diseases of the senile age that is most prevalent in the modern world. With regard to the population of people aged 60 years, the incidence of Alzheimer's disease is estimated at 1%, while in the population of people aged 90 and over even up to 50%. This type of dementia causes serious deficits in cognitive functions. From the neuroanatomical point of view, the changes taking place in the brain are the result of the disappearance of areas within the hippocampus, additionally, as one of the key causes of this disease, the accumulation of beta-amyloid in brain tissue is considered. The consequence of many changes is the loss of neurons, aggregation of amyloid plaques and the formation of tau protein into tangles. There are many hypotheses regarding the mechanisms and causes of the AD, but there are still many doubts about the existing health problem of older people. The aim of the study is to investigate the etiology and pathogenesis of AD in the context of the current state of knowledge and possible prognoses for the future in the light of research into this disease.http://www.ojs.ukw.edu.pl/index.php/johs/article/view/5198dementia, alzheimer's disease, etiology, pathogenesis
collection DOAJ
language English
format Article
sources DOAJ
author Grzegorz Wróbel
Paweł Zieliński
Jakub Spałek
spellingShingle Grzegorz Wróbel
Paweł Zieliński
Jakub Spałek
Alzheimer's disease - etiology and pathogenesis
Journal of Education, Health and Sport
dementia, alzheimer's disease, etiology, pathogenesis
author_facet Grzegorz Wróbel
Paweł Zieliński
Jakub Spałek
author_sort Grzegorz Wróbel
title Alzheimer's disease - etiology and pathogenesis
title_short Alzheimer's disease - etiology and pathogenesis
title_full Alzheimer's disease - etiology and pathogenesis
title_fullStr Alzheimer's disease - etiology and pathogenesis
title_full_unstemmed Alzheimer's disease - etiology and pathogenesis
title_sort alzheimer's disease - etiology and pathogenesis
publisher Kazimierz Wielki University
series Journal of Education, Health and Sport
issn 2391-8306
publishDate 2017-12-01
description Alzheimer's disease (AD) is one of the neurodegenerative diseases of the senile age that is most prevalent in the modern world. With regard to the population of people aged 60 years, the incidence of Alzheimer's disease is estimated at 1%, while in the population of people aged 90 and over even up to 50%. This type of dementia causes serious deficits in cognitive functions. From the neuroanatomical point of view, the changes taking place in the brain are the result of the disappearance of areas within the hippocampus, additionally, as one of the key causes of this disease, the accumulation of beta-amyloid in brain tissue is considered. The consequence of many changes is the loss of neurons, aggregation of amyloid plaques and the formation of tau protein into tangles. There are many hypotheses regarding the mechanisms and causes of the AD, but there are still many doubts about the existing health problem of older people. The aim of the study is to investigate the etiology and pathogenesis of AD in the context of the current state of knowledge and possible prognoses for the future in the light of research into this disease.
topic dementia, alzheimer's disease, etiology, pathogenesis
url http://www.ojs.ukw.edu.pl/index.php/johs/article/view/5198
work_keys_str_mv AT grzegorzwrobel alzheimersdiseaseetiologyandpathogenesis
AT pawełzielinski alzheimersdiseaseetiologyandpathogenesis
AT jakubspałek alzheimersdiseaseetiologyandpathogenesis
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