Evaluation of anti-plaque microbial activity of Azadirachta indica (neem oil) in vitro: A pilot study
Background: Probably microbial plaque is the main etiology for periodontal tissue inflammation. Various chemical agents have been evaluated over the years with respect to their antimicrobial effects in the oral cavity. However, all are associated with side effects that prohibit regular long-term use...
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Wolters Kluwer Medknow Publications
2012-01-01
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doaj-dca78e2dbb044cf1913f8c42e48a16f52020-11-24T23:34:11ZengWolters Kluwer Medknow PublicationsJournal of Pharmacy and Bioallied Sciences0975-74060976-48792012-01-014639439610.4103/0975-7406.100299Evaluation of anti-plaque microbial activity of Azadirachta indica (neem oil) in vitro: A pilot studySugumari ElavarasuP AbinayaS ElanchezhiyanThangakumaranK VennilaK B NaziyaBackground: Probably microbial plaque is the main etiology for periodontal tissue inflammation. Various chemical agents have been evaluated over the years with respect to their antimicrobial effects in the oral cavity. However, all are associated with side effects that prohibit regular long-term use. Therefore, the effectiveness of Azadirachta indica (neem) against plaque formation is considered to be vital, with lesser side effects. The aim of the present study is to evaluate and prove the antimicrobial activity of neem using plaque samples. Materials and Methods: Culture was prepared using brain heart infusion broth reagent. Dental plaque samples were used for that. Kirby-Bauer antimicrobial susceptibility test procedure was carried away with the sample. Neem oil was kept in the agar plate with culture and the diameter of inhibition zones was calculated. Results: Results showed inhibition zones on the agar plate around neem oil. Conclusion: Study shows definite antiplaque activity of neem oil.http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2012;volume=4;issue=6;spage=394;epage=396;aulast=ElavarasuAntimicrobialanti-plaque agentsherbalneem |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Sugumari Elavarasu P Abinaya S Elanchezhiyan Thangakumaran K Vennila K B Naziya |
spellingShingle |
Sugumari Elavarasu P Abinaya S Elanchezhiyan Thangakumaran K Vennila K B Naziya Evaluation of anti-plaque microbial activity of Azadirachta indica (neem oil) in vitro: A pilot study Journal of Pharmacy and Bioallied Sciences Antimicrobial anti-plaque agents herbal neem |
author_facet |
Sugumari Elavarasu P Abinaya S Elanchezhiyan Thangakumaran K Vennila K B Naziya |
author_sort |
Sugumari Elavarasu |
title |
Evaluation of anti-plaque microbial activity of Azadirachta indica (neem oil) in vitro: A pilot study |
title_short |
Evaluation of anti-plaque microbial activity of Azadirachta indica (neem oil) in vitro: A pilot study |
title_full |
Evaluation of anti-plaque microbial activity of Azadirachta indica (neem oil) in vitro: A pilot study |
title_fullStr |
Evaluation of anti-plaque microbial activity of Azadirachta indica (neem oil) in vitro: A pilot study |
title_full_unstemmed |
Evaluation of anti-plaque microbial activity of Azadirachta indica (neem oil) in vitro: A pilot study |
title_sort |
evaluation of anti-plaque microbial activity of azadirachta indica (neem oil) in vitro: a pilot study |
publisher |
Wolters Kluwer Medknow Publications |
series |
Journal of Pharmacy and Bioallied Sciences |
issn |
0975-7406 0976-4879 |
publishDate |
2012-01-01 |
description |
Background: Probably microbial plaque is the main etiology for periodontal tissue inflammation. Various chemical agents have been evaluated over the years with respect to their antimicrobial effects in the oral cavity. However, all are associated with side effects that prohibit regular long-term use. Therefore, the effectiveness of Azadirachta indica (neem) against plaque formation is considered to be vital, with lesser side effects. The aim of the present study is to evaluate and prove the antimicrobial activity of neem using plaque samples. Materials and Methods: Culture was prepared using brain heart infusion broth reagent. Dental plaque samples were used for that. Kirby-Bauer antimicrobial susceptibility test procedure was carried away with the sample. Neem oil was kept in the agar plate with culture and the diameter of inhibition zones was calculated. Results: Results showed inhibition zones on the agar plate around neem oil. Conclusion: Study shows definite antiplaque activity of neem oil. |
topic |
Antimicrobial anti-plaque agents herbal neem |
url |
http://www.jpbsonline.org/article.asp?issn=0975-7406;year=2012;volume=4;issue=6;spage=394;epage=396;aulast=Elavarasu |
work_keys_str_mv |
AT sugumarielavarasu evaluationofantiplaquemicrobialactivityofazadirachtaindicaneemoilinvitroapilotstudy AT pabinaya evaluationofantiplaquemicrobialactivityofazadirachtaindicaneemoilinvitroapilotstudy AT selanchezhiyan evaluationofantiplaquemicrobialactivityofazadirachtaindicaneemoilinvitroapilotstudy AT thangakumaran evaluationofantiplaquemicrobialactivityofazadirachtaindicaneemoilinvitroapilotstudy AT kvennila evaluationofantiplaquemicrobialactivityofazadirachtaindicaneemoilinvitroapilotstudy AT kbnaziya evaluationofantiplaquemicrobialactivityofazadirachtaindicaneemoilinvitroapilotstudy |
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