p47phox siRNA-Loaded PLGA Nanoparticles Suppress ROS/Oxidative Stress-Induced Chondrocyte Damage in Osteoarthritis

p47phox siRNA-Loaded PLGA Nanoparticles Suppress ROS/Oxidative Stress-Induced Chondrocyte Damage in Osteoarthritis

Osteoarthritis (OA) is the most common joint disorder that has had an increasing prevalence due to the aging of the population. Recent studies have concluded that OA progression is related to oxidative stress and reactive oxygen species (ROS). ROS are produced at low levels in articular chondrocytes...

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Bibliographic Details
Main Authors: Hyo Jung Shin, Hyewon Park, Nara Shin, Hyeok Hee Kwon, Yuhua Yin, Jeong-Ah Hwang, Song I Kim, Sang Ryong Kim, Sooil Kim, Yongbum Joo, Youngmo Kim, Jinhyun Kim, Jaewon Beom, Dong Woon Kim
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Polymers
Subjects:
osteoarthritis
monosodium iodoacetate
p47phox
plga nanoparticles
reactive oxygen species
Online Access:https://www.mdpi.com/2073-4360/12/2/443

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