Synaptic Diversity Suppresses Complex Collective Behavior in Networks of Theta Neurons

• Main Authors: Lucas Lin, Ernest Barreto, Paul So
• Format: Article
• Language: English
• Published: Frontiers Media S.A. 2020-05-01
• Series: Frontiers in Computational Neuroscience
• Subjects: network; synaptic diversity; theta neuron; oscillations; synchronization; heterogeneity
• Online Access: https://www.frontiersin.org/article/10.3389/fncom.2020.00044/full

Comprehending how the brain functions requires an understanding of the dynamics of neuronal assemblies. Previous work used a mean-field reduction method to determine the collective dynamics of a large heterogeneous network of uniformly and globally coupled theta neurons, which are a canonical formulation of Type I neurons. However, in modeling neuronal networks, it is unreasonable to assume that the coupling strength between every pair of neurons is identical. The goal in the present work is to analytically examine the collective macroscopic behavior of a network of theta neurons that is more realistic in that it includes heterogeneity in the coupling strength as well as in neuronal excitability. We consider the occurrence of dynamical structures that give rise to complicated dynamics via bifurcations of macroscopic collective quantities, concentrating on two biophysically relevant cases: (1) predominantly excitable neurons with mostly excitatory connections, and (2) predominantly spiking neurons with inhibitory connections. We find that increasing the synaptic diversity moves these dynamical structures to distant extremes of parameter space, leaving simple collective equilibrium states in the physiologically relevant region. We also study the node vs. focus nature of stable macroscopic equilibrium solutions and discuss our results in the context of recent literature.