On a Class of Optimal Type Covariate Adjusted Response Adaptive Allocations for Normal Treatment Responses

On a Class of Optimal Type Covariate Adjusted Response Adaptive Allocations for Normal Treatment Responses

In the context of clinical trials for comparing two treatments, a  new class of covariate adjusted  response adaptive procedures is developed to achieve a balance between clinical optimality and inferential precision. Assuming normally distributed responses, several exact and asymptotic properties a...

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Bibliographic Details
Main Authors: Rahul Bhattacharya, Uttam Bandyopadhyay
Format: Article
Language:English
Published: Austrian Statistical Society 2015-12-01
Series:Austrian Journal of Statistics
Online Access:http://www.ajs.or.at/index.php/ajs/article/view/69
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spelling doaj-dd08c62aa64742079faa3db82b30b9722021-04-22T12:35:02ZengAustrian Statistical SocietyAustrian Journal of Statistics1026-597X2015-12-0144410.17713/ajs.v44i4.69On a Class of Optimal Type Covariate Adjusted Response Adaptive Allocations for Normal Treatment ResponsesRahul BhattacharyaUttam BandyopadhyayIn the context of clinical trials for comparing two treatments, a  new class of covariate adjusted  response adaptive procedures is developed to achieve a balance between clinical optimality and inferential precision. Assuming normally distributed responses, several exact and asymptotic properties are studied and compared with a reasonable alternative under the presence of treatment covariate interaction.http://www.ajs.or.at/index.php/ajs/article/view/69
collection DOAJ
language English
format Article
sources DOAJ
author Rahul Bhattacharya
Uttam Bandyopadhyay
spellingShingle Rahul Bhattacharya
Uttam Bandyopadhyay
On a Class of Optimal Type Covariate Adjusted Response Adaptive Allocations for Normal Treatment Responses
Austrian Journal of Statistics
author_facet Rahul Bhattacharya
Uttam Bandyopadhyay
author_sort Rahul Bhattacharya
title On a Class of Optimal Type Covariate Adjusted Response Adaptive Allocations for Normal Treatment Responses
title_short On a Class of Optimal Type Covariate Adjusted Response Adaptive Allocations for Normal Treatment Responses
title_full On a Class of Optimal Type Covariate Adjusted Response Adaptive Allocations for Normal Treatment Responses
title_fullStr On a Class of Optimal Type Covariate Adjusted Response Adaptive Allocations for Normal Treatment Responses
title_full_unstemmed On a Class of Optimal Type Covariate Adjusted Response Adaptive Allocations for Normal Treatment Responses
title_sort on a class of optimal type covariate adjusted response adaptive allocations for normal treatment responses
publisher Austrian Statistical Society
series Austrian Journal of Statistics
issn 1026-597X
publishDate 2015-12-01
description In the context of clinical trials for comparing two treatments, a  new class of covariate adjusted  response adaptive procedures is developed to achieve a balance between clinical optimality and inferential precision. Assuming normally distributed responses, several exact and asymptotic properties are studied and compared with a reasonable alternative under the presence of treatment covariate interaction.
url http://www.ajs.or.at/index.php/ajs/article/view/69
work_keys_str_mv AT rahulbhattacharya onaclassofoptimaltypecovariateadjustedresponseadaptiveallocationsfornormaltreatmentresponses
AT uttambandyopadhyay onaclassofoptimaltypecovariateadjustedresponseadaptiveallocationsfornormaltreatmentresponses
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