Role of natural killer cells in isocitrate dehydrogenase 1/2 mutant glioma pathogenesis and emerging therapies

Role of natural killer cells in isocitrate dehydrogenase 1/2 mutant glioma pathogenesis and emerging therapies

Gliomas are the most common primary central nervous system malignancy and have an overall poor prognosis, despite aggressive treatment. Understanding the immune microenvironment of these fatal tumors will advance discovery of immune-related therapeutic targets. Natural killer (NK) cells are innate l...

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Bibliographic Details
Main Authors: Xiaoran Zhang, Aleksandra Safonova, Aparna Rao, Nduka Amankulor
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Glioma
Subjects:
Autologous cell transfer
glioblastoma
glioma
immune
immunotherapy
isocitrate dehydrogenase
microenvironment
natural killer cells
Online Access:http://www.jglioma.com/article.asp?issn=2589-6113;year=2019;volume=2;issue=3;spage=133;epage=138;aulast=Zhang

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