The adaptive transition of glioblastoma stem cells and its implications on treatments

Abstract Glioblastoma is the most malignant tumor occurring in the human central nervous system with overall median survival time <14.6 months. Current treatments such as chemotherapy and radiotherapy cannot reach an optimal remission since tumor resistance to therapy remains a challenge. Gliobla...

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Bibliographic Details
Main Authors: Zeyu Wang, Hao Zhang, Shengchao Xu, Zhixiong Liu, Quan Cheng
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-021-00491-w

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