Placental Mesenchymal Stromal Cells (PMSCs) and PMSC-Derived Extracellular Vesicles (PMSC-EVs) Attenuated Renal Fibrosis in Rats with Unilateral Ureteral Obstruction (UUO) by Regulating CD4+ T Cell Polarization
Purpose. Recent evidence has shown that CD4+ T helper (Th) cells are involved in renal inflammation and fibrosis. However, whether renal fibrosis can be alleviated by intervening in the polarization of CD4+ T cells remains unknown. Our research investigated the effects of intravenously administered...
Main Authors: | Zhu Zhu, Chaonan Han, Shuli Xian, Feng Zhuang, Feng Ding, Wei Zhang, Yingli Liu |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2020-01-01
|
Series: | Stem Cells International |
Online Access: | http://dx.doi.org/10.1155/2020/2685820 |
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