BRAFV600E-Associated Gene Expression Profile: Early Changes in the Transcriptome, Based on a Transgenic Mouse Model of Papillary Thyroid Carcinoma.

BRAFV600E-Associated Gene Expression Profile: Early Changes in the Transcriptome, Based on a Transgenic Mouse Model of Papillary Thyroid Carcinoma.

BACKGROUND:The molecular mechanisms driving the papillary thyroid carcinoma (PTC) are still poorly understood. The most frequent genetic alteration in PTC is the BRAFV600E mutation--its impact may extend even beyond PTC genomic profile and influence the tumor characteristics and even clinical behavi...

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Main Authors: Dagmara Rusinek, Michal Swierniak, Ewa Chmielik, Monika Kowal, Malgorzata Kowalska, Renata Cyplinska, Agnieszka Czarniecka, Wojciech Piglowski, Joanna Korfanty, Mykola Chekan, Jolanta Krajewska, Sylwia Szpak-Ulczok, Michal Jarzab, Wieslawa Widlak, Barbara Jarzab
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4666467?pdf=render

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