Hemolytic C-type lectin CEL-III from sea cucumber expressed in transgenic mosquitoes impairs malaria parasite development.
The midgut environment of anopheline mosquitoes plays an important role in the development of the malaria parasite. Using genetic manipulation of anopheline mosquitoes to change the environment in the mosquito midgut may inhibit development of the malaria parasite, thus blocking malaria transmission...
Main Authors: | Shigeto Yoshida, Yohei Shimada, Daisuke Kondoh, Yoshiaki Kouzuma, Anil K Ghosh, Marcelo Jacobs-Lorena, Robert E Sinden |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2007-12-01
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Series: | PLoS Pathogens |
Online Access: | https://doi.org/10.1371/journal.ppat.0030192 |
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