A Validation Study of the Japanese Version of the Addenbrooke’s Cognitive Examination-Revised

• Main Authors: Kelssy Hitomi dos Santos Kawata, Ryusaku Hashimoto, Yoshiyuki Nishio, Atsuko Hayashi, Nanayo Ogawa, Shigenori Kanno, Kotaro Hiraoka, Kayoko Yokoi, Osamu Iizuka, Etsuro Mori
• Format: Article
• Language: English
• Published: Karger Publishers 2012-03-01
• Series: Dementia and Geriatric Cognitive Disorders Extra
• Subjects: Addenbrooke’s Cognitive Examination-Revised; Mini-Mental State Examination; Dementia; Screening; Validity; Reliability; Diagnostic accuracy; Normative data
• Online Access: http://www.karger.com/Article/FullText/336909
• ISSN: 1664-5464

The aim of this study was to validate the Japanese version of the Addenbrooke’s Cognitive Examination-Revised (ACE-R) [Mori: Japanese Edition of Hodges JR’s Cognitive Assessment for Clinicians, 2010] designed to detect dementia, and to compare its diagnostic accuracy with that of the Mini-Mental State Examination. The ACE-R was administered to 85 healthy individuals and 126 patients with dementia. The reliability assessment revealed a strong correlation in both groups. The internal consistency was excellent (α-coefficient = 0.88). Correlation with the Clinical Dementia Rating sum of boxes score was significant (rs = –0.61, p < 0.001). The area under the curve was 0.98 for the ACE-R and 0.96 for the Mini-Mental State Examination. The cut-off score of 80 showed a sensitivity of 94% and a specificity of 94%. Like the original ACE-R and the versions designed for other languages, the Japanese version of the ACE-R is a reliable and valid test for the detection of dementia.