Transcription driven somatic DNA methylation within the imprinted Gnas cluster.
Differential marking of genes in female and male gametes by DNA methylation is essential to genomic imprinting. In female gametes transcription traversing differentially methylated regions (DMRs) is a common requirement for de novo methylation at DMRs. At the imprinted Gnas cluster oocyte specific t...
Main Authors: | Stuti Mehta, Christine M Williamson, Simon Ball, Charlotte Tibbit, Colin Beechey, Martin Fray, Jo Peters |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4319783?pdf=render |
Similar Items
-
Uncoupling antisense-mediated silencing and DNA methylation in the imprinted Gnas cluster.
by: Christine M Williamson, et al.
Published: (2011-03-01) -
Imprinting at the mouse Gnas cluster
by: Mehta, Stuti Rushikant
Published: (2012) -
Antisense Activity across the Nesp Promoter is Required for Nespas-Mediated Silencing in the Imprinted Gnas Cluster
by: Charlotte J. Tibbit, et al.
Published: (2015-11-01) -
Gene Dosage Effects at the Imprinted Gnas Cluster.
by: Simon T Ball, et al.
Published: (2013-01-01) -
Investigating the role of transcription events in establishing methylation imprint marks at the Gnas locus
by: Chotalia, Mita
Published: (2009)