STAT3 Activation in Pressure-Overloaded Feline Myocardium: Role for Integrins and the Tyrosine Kinase BMX

<p>Growth, survival and cytoskeletal rearrangement of cardiomyocytes are critical for cardiac hypertrophy. Signal transducer and activator of transcription-3 (STAT3) activation is an important cardioprotective factor associated with cardiac hypertrophy. Although STAT3 activation has been repor...

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Bibliographic Details
Main Author: Christopher D. Willey, Arun P. Palanisamy, Rebecca K. Johnston, Santhosh K. Mani, Hirokazu Shiraishi, William J. Tuxworth, Michael R. Zile, Sundaravadivel Balasubramanian, Dhandapani Kuppuswamy
Format: Article
Language:English
Published: Ivyspring International Publisher 2008-01-01
Series:International Journal of Biological Sciences
Online Access:http://www.biolsci.org/v04p0184.htm