Altered bioavailability of epoxyeicosatrienoic acids is associated with conduit artery endothelial dysfunction in type 2 diabetic patients

Altered bioavailability of epoxyeicosatrienoic acids is associated with conduit artery endothelial dysfunction in type 2 diabetic patients

Abstract Background This pathophysiological study addressed the hypothesis that soluble epoxide hydrolase (sEH), which metabolizes the vasodilator and anti-inflammatory epoxyeicosatrienoic acids (EETs) to dihydroxyeicosatrienoic acids (DHETs), contributes to conduit artery endothelial dysfunction in...

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Bibliographic Details
Main Authors: Thomas Duflot, Lucile Moreau-Grangé, Clothilde Roche, Michèle Iacob, Julien Wils, Isabelle Rémy-Jouet, Anne-Françoise Cailleux, Matthieu Leuillier, Sylvanie Renet, Dongyang Li, Christophe Morisseau, Fabien Lamoureux, Vincent Richard, Gaëtan Prévost, Robinson Joannidès, Jérémy Bellien
Format: Article
Language:English
Published: BMC 2019-03-01
Series:Cardiovascular Diabetology
Subjects:
Type 2 diabetes
Endothelial dysfunction
Soluble epoxide hydrolase
Epoxyeicosatrienoic acids
Online Access:http://link.springer.com/article/10.1186/s12933-019-0843-z

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http://link.springer.com/article/10.1186/s12933-019-0843-z

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