MiR-130a-3p Alleviates Liver Fibrosis by Suppressing HSCs Activation and Skewing Macrophage to Ly6Clo Phenotype

MiR-130a-3p Alleviates Liver Fibrosis by Suppressing HSCs Activation and Skewing Macrophage to Ly6Clo Phenotype

Emerging evidences have highlighted the crucial role of microRNAs (miRNAs) in the liver cirrhosis, but the relationship between miR-130a-3p and liver cirrhosis is not entirely clear. As we all know, schistosomiasis, as one of the zoonoses, can lead to liver cirrhosis when it advances. In this study,...

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Bibliographic Details
Main Authors: Lei Liu, Peng Wang, Yun-Sheng Wang, Ya-Nan Zhang, Chen Li, Zi-Yin Yang, Zi-Hao Liu, Ting-Zheng Zhan, Jing Xu, Chao-Ming Xia
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Immunology
Subjects:
liver fibrosis
miR-130a-3p
Ly6Clo
HSCs
schistosomiasis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.696069/full

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