NAD+ augmentation with nicotinamide riboside improves lymphoid potential of Atm −/− and old mice HSCs
Abstract NAD+ supplementation has significant benefits in compromised settings, acting largely through improved mitochondrial function and DNA repair. Elevating NAD+ to physiological levels has been shown to improve the function of some adult stem cells, with implications that these changes will lea...
Main Authors: | Le Zong, Mayuri Tanaka-Yano, Bongsoo Park, Hagai Yanai, Ferda T. Turhan, Deborah L. Croteau, Jane Tian, Evandro F. Fang, Vilhelm A. Bohr, Isabel Beerman |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-09-01
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Series: | npj Aging and Mechanisms of Disease |
Online Access: | https://doi.org/10.1038/s41514-021-00078-3 |
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