From simple to supercomplex: mitochondrial genomes of euglenozoan protists [version 2; referees: 2 approved]
Mitochondria are double membrane organelles of endosymbiotic origin, best known for constituting the centre of energetics of a eukaryotic cell. They contain their own mitochondrial genome, which as a consequence of gradual reduction during evolution typically contains less than two dozens of genes....
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
F1000 Research Ltd
2016-11-01
|
Series: | F1000Research |
Subjects: | |
Online Access: | https://f1000research.com/articles/5-392/v2 |
id |
doaj-de277d2446fc4be8b306392ad92f73fd |
---|---|
record_format |
Article |
spelling |
doaj-de277d2446fc4be8b306392ad92f73fd2020-11-25T01:23:36ZengF1000 Research LtdF1000Research2046-14022016-11-01510.12688/f1000research.8040.210989From simple to supercomplex: mitochondrial genomes of euglenozoan protists [version 2; referees: 2 approved]Drahomíra Faktorová0Eva Dobáková1Priscila Peña-Diaz2Julius Lukeš3Institute of Parasitology, Biology Centre, Czech Academy of Sciences, České Budějovice (Budweis), Czech RepublicInstitute of Parasitology, Biology Centre, Czech Academy of Sciences, České Budějovice (Budweis), Czech RepublicInstitute of Parasitology, Biology Centre, Czech Academy of Sciences, České Budějovice (Budweis), Czech RepublicInstitute of Parasitology, Biology Centre, Czech Academy of Sciences, České Budějovice (Budweis), Czech RepublicMitochondria are double membrane organelles of endosymbiotic origin, best known for constituting the centre of energetics of a eukaryotic cell. They contain their own mitochondrial genome, which as a consequence of gradual reduction during evolution typically contains less than two dozens of genes. In this review, we highlight the extremely diverse architecture of mitochondrial genomes and mechanisms of gene expression between the three sister groups constituting the phylum Euglenozoa - Euglenida, Diplonemea and Kinetoplastea. The earliest diverging euglenids possess a simplified mitochondrial genome and a conventional gene expression, whereas both are highly complex in the two other groups. The expression of their mitochondrial-encoded proteins requires extensive post-transcriptional modifications guided by complex protein machineries and multiple small RNA molecules. Moreover, the least studied diplonemids, which have been recently discovered as a highly abundant component of the world ocean plankton, possess one of the most complicated mitochondrial genome organisations known to date.https://f1000research.com/articles/5-392/v2BioinformaticsControl of Gene ExpressionDevelopmental EvolutionGenomicsMembranes & SortingMicrobial Evolution & GenomicsParasitologyPlant Cell BiologyPlant Genomes & Evolution |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Drahomíra Faktorová Eva Dobáková Priscila Peña-Diaz Julius Lukeš |
spellingShingle |
Drahomíra Faktorová Eva Dobáková Priscila Peña-Diaz Julius Lukeš From simple to supercomplex: mitochondrial genomes of euglenozoan protists [version 2; referees: 2 approved] F1000Research Bioinformatics Control of Gene Expression Developmental Evolution Genomics Membranes & Sorting Microbial Evolution & Genomics Parasitology Plant Cell Biology Plant Genomes & Evolution |
author_facet |
Drahomíra Faktorová Eva Dobáková Priscila Peña-Diaz Julius Lukeš |
author_sort |
Drahomíra Faktorová |
title |
From simple to supercomplex: mitochondrial genomes of euglenozoan protists [version 2; referees: 2 approved] |
title_short |
From simple to supercomplex: mitochondrial genomes of euglenozoan protists [version 2; referees: 2 approved] |
title_full |
From simple to supercomplex: mitochondrial genomes of euglenozoan protists [version 2; referees: 2 approved] |
title_fullStr |
From simple to supercomplex: mitochondrial genomes of euglenozoan protists [version 2; referees: 2 approved] |
title_full_unstemmed |
From simple to supercomplex: mitochondrial genomes of euglenozoan protists [version 2; referees: 2 approved] |
title_sort |
from simple to supercomplex: mitochondrial genomes of euglenozoan protists [version 2; referees: 2 approved] |
publisher |
F1000 Research Ltd |
series |
F1000Research |
issn |
2046-1402 |
publishDate |
2016-11-01 |
description |
Mitochondria are double membrane organelles of endosymbiotic origin, best known for constituting the centre of energetics of a eukaryotic cell. They contain their own mitochondrial genome, which as a consequence of gradual reduction during evolution typically contains less than two dozens of genes. In this review, we highlight the extremely diverse architecture of mitochondrial genomes and mechanisms of gene expression between the three sister groups constituting the phylum Euglenozoa - Euglenida, Diplonemea and Kinetoplastea. The earliest diverging euglenids possess a simplified mitochondrial genome and a conventional gene expression, whereas both are highly complex in the two other groups. The expression of their mitochondrial-encoded proteins requires extensive post-transcriptional modifications guided by complex protein machineries and multiple small RNA molecules. Moreover, the least studied diplonemids, which have been recently discovered as a highly abundant component of the world ocean plankton, possess one of the most complicated mitochondrial genome organisations known to date. |
topic |
Bioinformatics Control of Gene Expression Developmental Evolution Genomics Membranes & Sorting Microbial Evolution & Genomics Parasitology Plant Cell Biology Plant Genomes & Evolution |
url |
https://f1000research.com/articles/5-392/v2 |
work_keys_str_mv |
AT drahomirafaktorova fromsimpletosupercomplexmitochondrialgenomesofeuglenozoanprotistsversion2referees2approved AT evadobakova fromsimpletosupercomplexmitochondrialgenomesofeuglenozoanprotistsversion2referees2approved AT priscilapenadiaz fromsimpletosupercomplexmitochondrialgenomesofeuglenozoanprotistsversion2referees2approved AT juliuslukes fromsimpletosupercomplexmitochondrialgenomesofeuglenozoanprotistsversion2referees2approved |
_version_ |
1725121134072954880 |