In Vitro Drug Release, Permeability, and Structural Test of Ciprofloxacin-Loaded Nanofibers

In Vitro Drug Release, Permeability, and Structural Test of Ciprofloxacin-Loaded Nanofibers

Nanofibers of the poorly water-soluble antibiotic ciprofloxacin (CIP) were fabricated in the form of an amorphous solid dispersion by using poly(vinyl pyrrolidone) as a polymer matrix, by the low-cost electrospinning method. The solubility of the nanofibers as well as their in vitro diffusion were r...

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Bibliographic Details
Main Authors: Luca Éva Uhljar, Sheng Yuan Kan, Norbert Radacsi, Vasileios Koutsos, Piroska Szabó-Révész, Rita Ambrus
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Pharmaceutics
Subjects:
amorphous solid dispersion
ciprofloxacin
electrospinning
nanofibers
poorly water-soluble drug
povidone
Online Access:https://www.mdpi.com/1999-4923/13/4/556

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