Interaction of the mu-opioid receptor with GPR177 (Wntless) inhibits Wnt secretion: potential implications for opioid dependence

Interaction of the mu-opioid receptor with GPR177 (Wntless) inhibits Wnt secretion: potential implications for opioid dependence

<p>Abstract</p> <p>Background</p> <p>Opioid agonist drugs produce analgesia. However, long-term exposure to opioid agonists may lead to opioid dependence. The analgesic and addictive properties of opioid agonist drugs are mediated primarily via the mu-opioid receptor (M...

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Bibliographic Details
Main Authors:	Stagljar Igor, Van Bockstaele Elisabeth J, Reyes Beverly AS, Wong Victoria, Kittanakom Saranya, Jin Jay, Berrettini Wade, Levenson Robert
Format:	Article
Language:	English
Published:	BMC 2010-03-01
Series:	BMC Neuroscience
Online Access:	http://www.biomedcentral.com/1471-2202/11/33

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