Trypanosomatid selenophosphate synthetase structure, function and interaction with selenocysteine lyase.

Eukaryotes from the Excavata superphylum have been used as models to study the evolution of cellular molecular processes. Strikingly, human parasites of the Trypanosomatidae family (T. brucei, T. cruzi and L. major) conserve the complex machinery responsible for selenocysteine biosynthesis and incor...

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Bibliographic Details
Main Authors: Marco Túlio Alves da Silva, Ivan Rosa E Silva, Lívia Maria Faim, Natália Karla Bellini, Murilo Leão Pereira, Ana Laura Lima, Teresa Cristina Leandro de Jesus, Fernanda Cristina Costa, Tatiana Faria Watanabe, Humberto D'Muniz Pereira, Sandro Roberto Valentini, Cleslei Fernando Zanelli, Júlio Cesar Borges, Marcio Vinicius Bertacine Dias, Júlia Pinheiro Chagas da Cunha, Bidyottam Mittra, Norma W Andrews, Otavio Henrique Thiemann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-10-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0008091

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