Next Generation Sequencing of miRNAs – Strategies, Resources and Methods

Next Generation Sequencing of miRNAs – Strategies, Resources and Methods

miRNAs constitute a family of small RNA species that have been demonstrated to play a central role in regulating gene expression in many organisms. With the advent of next generation sequencing, new opportunities have arisen to identify and quantify miRNAs and elucidate their function. The unprecede...

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Bibliographic Details
Main Authors: Susanne Motameny, Stefanie Wolters, Peter Nürnberg, Björn Schumacher
Format: Article
Language:English
Published: MDPI AG 2010-06-01
Series:Genes
Subjects:
miRNA
next generation sequencing
Online Access:http://www.mdpi.com/2073-4425/1/1/70/
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spelling doaj-de58b541ea0747168c2c871b0b6f549f2020-11-25T01:15:43ZengMDPI AGGenes2073-44252010-06-0111708410.3390/genes1010070Next Generation Sequencing of miRNAs – Strategies, Resources and MethodsSusanne MotamenyStefanie WoltersPeter NürnbergBjörn SchumachermiRNAs constitute a family of small RNA species that have been demonstrated to play a central role in regulating gene expression in many organisms. With the advent of next generation sequencing, new opportunities have arisen to identify and quantify miRNAs and elucidate their function. The unprecedented sequencing depth reached by next generation sequencing technologies makes it possible to get a comprehensive miRNA landscape but also poses new challenges for data analysis. We provide an overview of strategies used for miRNA sequencing, public miRNA resources, and useful methods and tools that are available for data analysis. http://www.mdpi.com/2073-4425/1/1/70/miRNAnext generation sequencing
collection DOAJ
language English
format Article
sources DOAJ
author Susanne Motameny
Stefanie Wolters
Peter Nürnberg
Björn Schumacher
spellingShingle Susanne Motameny
Stefanie Wolters
Peter Nürnberg
Björn Schumacher
Next Generation Sequencing of miRNAs – Strategies, Resources and Methods
Genes
miRNA
next generation sequencing
author_facet Susanne Motameny
Stefanie Wolters
Peter Nürnberg
Björn Schumacher
author_sort Susanne Motameny
title Next Generation Sequencing of miRNAs – Strategies, Resources and Methods
title_short Next Generation Sequencing of miRNAs – Strategies, Resources and Methods
title_full Next Generation Sequencing of miRNAs – Strategies, Resources and Methods
title_fullStr Next Generation Sequencing of miRNAs – Strategies, Resources and Methods
title_full_unstemmed Next Generation Sequencing of miRNAs – Strategies, Resources and Methods
title_sort next generation sequencing of mirnas – strategies, resources and methods
publisher MDPI AG
series Genes
issn 2073-4425
publishDate 2010-06-01
description miRNAs constitute a family of small RNA species that have been demonstrated to play a central role in regulating gene expression in many organisms. With the advent of next generation sequencing, new opportunities have arisen to identify and quantify miRNAs and elucidate their function. The unprecedented sequencing depth reached by next generation sequencing technologies makes it possible to get a comprehensive miRNA landscape but also poses new challenges for data analysis. We provide an overview of strategies used for miRNA sequencing, public miRNA resources, and useful methods and tools that are available for data analysis.
topic miRNA
next generation sequencing
url http://www.mdpi.com/2073-4425/1/1/70/
work_keys_str_mv AT susannemotameny nextgenerationsequencingofmirnasstrategiesresourcesandmethods
AT stefaniewolters nextgenerationsequencingofmirnasstrategiesresourcesandmethods
AT peternurnberg nextgenerationsequencingofmirnasstrategiesresourcesandmethods
AT bjornschumacher nextgenerationsequencingofmirnasstrategiesresourcesandmethods
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