The in vitro micronucleus assay using imaging flow cytometry and deep learning

The in vitro micronucleus assay using imaging flow cytometry and deep learning

Abstract The in vitro micronucleus (MN) assay is a well-established assay for quantification of DNA damage, and is required by regulatory bodies worldwide to screen chemicals for genetic toxicity. The MN assay is performed in two variations: scoring MN in cytokinesis-blocked binucleated cells or dir...

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Bibliographic Details
Main Authors:	Matthew A. Rodrigues, Christine E. Probst, Artiom Zayats, Bryan Davidson, Michael Riedel, Yang Li, Vidya Venkatachalam
Format:	Article
Language:	English
Published:	Nature Publishing Group 2021-05-01
Series:	npj Systems Biology and Applications
Online Access:	https://doi.org/10.1038/s41540-021-00179-5

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