Analysis of long-range correlation in sequences data of proteins

• Main Authors: Isvoran Adriana, Unipan Laura, Craciun Dana, Morariu Vasile
• Format: Article
• Language: English
• Published: Serbian Chemical Society 2007-01-01
• Series: Journal of the Serbian Chemical Society
• Subjects: sequences of proteins; long-range correlation; spectral coefficient; scaling exponent; hurst coefficient
• Online Access: http://www.doiserbia.nb.rs/img/doi/0352-5139/2007/0352-51390704383I.pdf

The results presented here suggest the existence of correlations in the sequence data of proteins. 32 proteins, both globular and fibrous, both monomeric and polymeric, were analyzed. The primary structures of these proteins were treated as time series. Three spatial series of data for each sequence of a protein were generated from numerical correspondences between each amino acid and a physical property associated with it, i.e., its electric charge, its polar character and its dipole moment. For each series, the spectral coefficient, the scaling exponent and the Hurst coefficient were determined. The values obtained for these coefficients revealed non-randomness in the series of data. .