Prolonged Systemic Inflammation Alters Muscarinic Long-Term Potentiation (mLTP) in the Hippocampus

The cholinergic system plays a fundamental role in learning and memory. Pharmacological activation of the muscarinic receptor M1R potentiates NMDA receptor activity and induces short-term potentiation at the synapses called muscarinic LTP, mLTP. Dysfunction of cholinergic transmission has been detec...

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Bibliographic Details
Main Authors: Efrat Shavit-Stein, Amir Dori, Marina Ben Shimon, Shany Guly Gofrit, Nicola Maggio
Format: Article
Language:English
Published: Hindawi Limited 2021-01-01
Series:Neural Plasticity
Online Access:http://dx.doi.org/10.1155/2021/8813734