Prolonged Systemic Inflammation Alters Muscarinic Long-Term Potentiation (mLTP) in the Hippocampus
The cholinergic system plays a fundamental role in learning and memory. Pharmacological activation of the muscarinic receptor M1R potentiates NMDA receptor activity and induces short-term potentiation at the synapses called muscarinic LTP, mLTP. Dysfunction of cholinergic transmission has been detec...
Main Authors: | Efrat Shavit-Stein, Amir Dori, Marina Ben Shimon, Shany Guly Gofrit, Nicola Maggio |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2021-01-01
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Series: | Neural Plasticity |
Online Access: | http://dx.doi.org/10.1155/2021/8813734 |
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