Synthesis and characterization of novel biological tetracoumarin derivatives bearing ether moieties
A series of novel tetracoumarin derivatives (3a-f) were prepared using the reaction of ether functionalized dibenzaldehyde with 4-hydroxycoumarin in the presence of sodium acetate. The structure of compounds was validated by IR, NMR, and CHN analyzes. Antimicrobial (antibacterial and antifungal) act...
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De Gruyter
2020-04-01
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doaj-de97d8fbcb43479d8b283b8f61b363452021-02-28T21:53:15ZengDe GruyterHeterocyclic Communications2191-01972020-04-01261606710.1515/hc-2020-0009hc-2020-0009Synthesis and characterization of novel biological tetracoumarin derivatives bearing ether moietiesBehzadi Soheila Asadpour0Sheikhhosseini Enayatollah1Ahmadi Sayed Ali2Ghazanfari Dadkhoda3Akhgar Mohammadreza4Department of Chemistry, Kerman Branch, Islamic Azad University, Kerman, IranDepartment of Chemistry, Kerman Branch, Islamic Azad University, Kerman, IranDepartment of Chemistry, Kerman Branch, Islamic Azad University, Kerman, IranDepartment of Chemistry, Kerman Branch, Islamic Azad University, Kerman, IranDepartment of Chemistry, Kerman Branch, Islamic Azad University, Kerman, IranA series of novel tetracoumarin derivatives (3a-f) were prepared using the reaction of ether functionalized dibenzaldehyde with 4-hydroxycoumarin in the presence of sodium acetate. The structure of compounds was validated by IR, NMR, and CHN analyzes. Antimicrobial (antibacterial and antifungal) activity was studied on the basis of the minimum bactericidal concentration, minimum inhibitory concentration and inhibitory zone diameter. Favorable biological activity was found in compound 3f.http://www.degruyter.com/view/j/hc.2020.26.issue-1/hc-2020-0009/hc-2020-0009.xml?format=INTtetracoumarin4-hydroxycoumarinaqueous mediaethylene ether spacerbiological activity |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Behzadi Soheila Asadpour Sheikhhosseini Enayatollah Ahmadi Sayed Ali Ghazanfari Dadkhoda Akhgar Mohammadreza |
spellingShingle |
Behzadi Soheila Asadpour Sheikhhosseini Enayatollah Ahmadi Sayed Ali Ghazanfari Dadkhoda Akhgar Mohammadreza Synthesis and characterization of novel biological tetracoumarin derivatives bearing ether moieties Heterocyclic Communications tetracoumarin 4-hydroxycoumarin aqueous media ethylene ether spacer biological activity |
author_facet |
Behzadi Soheila Asadpour Sheikhhosseini Enayatollah Ahmadi Sayed Ali Ghazanfari Dadkhoda Akhgar Mohammadreza |
author_sort |
Behzadi Soheila Asadpour |
title |
Synthesis and characterization of novel biological tetracoumarin derivatives bearing ether moieties |
title_short |
Synthesis and characterization of novel biological tetracoumarin derivatives bearing ether moieties |
title_full |
Synthesis and characterization of novel biological tetracoumarin derivatives bearing ether moieties |
title_fullStr |
Synthesis and characterization of novel biological tetracoumarin derivatives bearing ether moieties |
title_full_unstemmed |
Synthesis and characterization of novel biological tetracoumarin derivatives bearing ether moieties |
title_sort |
synthesis and characterization of novel biological tetracoumarin derivatives bearing ether moieties |
publisher |
De Gruyter |
series |
Heterocyclic Communications |
issn |
2191-0197 |
publishDate |
2020-04-01 |
description |
A series of novel tetracoumarin derivatives (3a-f) were prepared using the reaction of ether functionalized dibenzaldehyde with 4-hydroxycoumarin in the presence of sodium acetate. The structure of compounds was validated by IR, NMR, and CHN analyzes. Antimicrobial (antibacterial and antifungal) activity was studied on the basis of the minimum bactericidal concentration, minimum inhibitory concentration and inhibitory zone diameter. Favorable biological activity was found in compound 3f. |
topic |
tetracoumarin 4-hydroxycoumarin aqueous media ethylene ether spacer biological activity |
url |
http://www.degruyter.com/view/j/hc.2020.26.issue-1/hc-2020-0009/hc-2020-0009.xml?format=INT |
work_keys_str_mv |
AT behzadisoheilaasadpour synthesisandcharacterizationofnovelbiologicaltetracoumarinderivativesbearingethermoieties AT sheikhhosseinienayatollah synthesisandcharacterizationofnovelbiologicaltetracoumarinderivativesbearingethermoieties AT ahmadisayedali synthesisandcharacterizationofnovelbiologicaltetracoumarinderivativesbearingethermoieties AT ghazanfaridadkhoda synthesisandcharacterizationofnovelbiologicaltetracoumarinderivativesbearingethermoieties AT akhgarmohammadreza synthesisandcharacterizationofnovelbiologicaltetracoumarinderivativesbearingethermoieties |
_version_ |
1724247542728753152 |