Age-Related Gene Expression Signature in Rats Demonstrate Early, Late, and Linear Transcriptional Changes from Multiple Tissues
Summary: To understand the changes in gene expression that occur as a result of age, which might create a permissive or causal environment for age-related diseases, we produce a multi-time point age-related gene expression signature (AGES) from liver, kidney, skeletal muscle, and hippocampus of rats...
Main Authors: | Tea Shavlakadze, Melody Morris, Jian Fang, Sharon X. Wang, Jiang Zhu, Weihua Zhou, Herman W. Tse, Ricardo Mondragon-Gonzalez, Guglielmo Roma, David J. Glass |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2019-09-01
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Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124719310915 |
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