Japonicone V, a sesquiterpene lactone derivative from the flowers of Inula japonica, inhibits hepatitis E virus replication by targeting virus-associated autophagy

Japonicone V, a sesquiterpene lactone derivative from the flowers of Inula japonica, inhibits hepatitis E virus replication by targeting virus-associated autophagy

Hepatitis E virus (HEV) is one of the major causes of acute hepatitis worldwide. Here, we investigated the role of autophagy on HEV replication and demonstrated anti-HEV effects of japonicone V, a main constituent of the flowers of Inula japonica. Results showed that HEV infection induced autophagy...

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Bibliographic Details
Main Authors: Yueliang Zhao, Mengru Tao, Ru Wang, Yuanqiang Guo, Mingfu Wang
Format: Article
Language:English
Published: Elsevier 2020-02-01
Series:Journal of Functional Foods
Subjects:
Inula japonica
Japonicone V
HEV replication
Autophagy
Signaling pathway
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464619306796

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http://www.sciencedirect.com/science/article/pii/S1756464619306796

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