Microflora of bile aspirates in patients with acute cholecystitis With or without cholelithiasis: a tropical experience
The current study determined the spectrum of biliary microflora with special emphasis on enteric fever organisms in patients with acute cholangitis with and without cholelithiasis or other biliary diseases. The patients were divided into three groups: Group A consisted of patients with acute cholecy...
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doaj-dec91696f9c540ac9612e0d91404f6632020-11-25T02:56:49ZengElsevierBrazilian Journal of Infectious Diseases1678-439112322222510.1590/S1413-86702008000300012S1413-86702008000300012Microflora of bile aspirates in patients with acute cholecystitis With or without cholelithiasis: a tropical experienceMalini R. Capoor0Deepthi Nair1Rajni2Geetika Khanna3S.V. Krishna4M.S. Chintamani5Pushpa Aggarwal6Vardhman Mahaveer Medical College & Safdarjung HospitalVardhman Mahaveer Medical College & Safdarjung HospitalVardhman Mahaveer Medical College & Safdarjung HospitalVardhman Mahaveer Medical College & Safdarjung HospitalVardhman Mahaveer Medical College & Safdarjung HospitalVardhman Mahaveer Medical College & Safdarjung HospitalVardhman Mahaveer Medical College & Safdarjung HospitalThe current study determined the spectrum of biliary microflora with special emphasis on enteric fever organisms in patients with acute cholangitis with and without cholelithiasis or other biliary diseases. The patients were divided into three groups: Group A consisted of patients with acute cholecystitis with cholelithiasis; Group B consisted of patients with acute cholecystitis with gastrointestinal ailments requiring biliary drainage and group C consisted of patients with gallbladder carcinoma. Gallbladder, bile and gallstones were subjected to complete microbiological and histopathological examination. Antimicrobial susceptibility of the isolates was performed as per CLSI guidelines. Bacteria were recovered from 17 samples (32%) in Group A, 17 (51.4%) in Group B and 1 (1.6%) in Group C. The most common organisms isolated were Escherichia coli (11, 29.7%), Klebsiella pneumoniae (10, 27%), Citrobacter freundii (3, 8.1%), Salmonella enterica serovar Typhi (3, 8.1%), etc. The majority of Enterobacteriaceae isolates were susceptible to piperacillin-tazobactam and meropenem. As regards Salmonella spp., S. Typhi was isolated from 2 (3.8%) patients in Group A and 1 (16%) in Group C. Antimicrobial susceptibility of potential causative organisms, the severity of the cholecystitis, and the local susceptibility pattern must be taken into consideration when prescribing drugs. A protocol regarding the management of such cases should be formulated based on observations of similar studies.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702008000300012&lng=en&tlng=enBileacute cholecystitisSalmonella enretica serovar Typhi |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Malini R. Capoor Deepthi Nair Rajni Geetika Khanna S.V. Krishna M.S. Chintamani Pushpa Aggarwal |
spellingShingle |
Malini R. Capoor Deepthi Nair Rajni Geetika Khanna S.V. Krishna M.S. Chintamani Pushpa Aggarwal Microflora of bile aspirates in patients with acute cholecystitis With or without cholelithiasis: a tropical experience Brazilian Journal of Infectious Diseases Bile acute cholecystitis Salmonella enretica serovar Typhi |
author_facet |
Malini R. Capoor Deepthi Nair Rajni Geetika Khanna S.V. Krishna M.S. Chintamani Pushpa Aggarwal |
author_sort |
Malini R. Capoor |
title |
Microflora of bile aspirates in patients with acute cholecystitis With or without cholelithiasis: a tropical experience |
title_short |
Microflora of bile aspirates in patients with acute cholecystitis With or without cholelithiasis: a tropical experience |
title_full |
Microflora of bile aspirates in patients with acute cholecystitis With or without cholelithiasis: a tropical experience |
title_fullStr |
Microflora of bile aspirates in patients with acute cholecystitis With or without cholelithiasis: a tropical experience |
title_full_unstemmed |
Microflora of bile aspirates in patients with acute cholecystitis With or without cholelithiasis: a tropical experience |
title_sort |
microflora of bile aspirates in patients with acute cholecystitis with or without cholelithiasis: a tropical experience |
publisher |
Elsevier |
series |
Brazilian Journal of Infectious Diseases |
issn |
1678-4391 |
description |
The current study determined the spectrum of biliary microflora with special emphasis on enteric fever organisms in patients with acute cholangitis with and without cholelithiasis or other biliary diseases. The patients were divided into three groups: Group A consisted of patients with acute cholecystitis with cholelithiasis; Group B consisted of patients with acute cholecystitis with gastrointestinal ailments requiring biliary drainage and group C consisted of patients with gallbladder carcinoma. Gallbladder, bile and gallstones were subjected to complete microbiological and histopathological examination. Antimicrobial susceptibility of the isolates was performed as per CLSI guidelines. Bacteria were recovered from 17 samples (32%) in Group A, 17 (51.4%) in Group B and 1 (1.6%) in Group C. The most common organisms isolated were Escherichia coli (11, 29.7%), Klebsiella pneumoniae (10, 27%), Citrobacter freundii (3, 8.1%), Salmonella enterica serovar Typhi (3, 8.1%), etc. The majority of Enterobacteriaceae isolates were susceptible to piperacillin-tazobactam and meropenem. As regards Salmonella spp., S. Typhi was isolated from 2 (3.8%) patients in Group A and 1 (16%) in Group C. Antimicrobial susceptibility of potential causative organisms, the severity of the cholecystitis, and the local susceptibility pattern must be taken into consideration when prescribing drugs. A protocol regarding the management of such cases should be formulated based on observations of similar studies. |
topic |
Bile acute cholecystitis Salmonella enretica serovar Typhi |
url |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702008000300012&lng=en&tlng=en |
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