Inhibition of myostatin prevents microgravity-induced loss of skeletal muscle mass and strength.

Inhibition of myostatin prevents microgravity-induced loss of skeletal muscle mass and strength.

The microgravity conditions of prolonged spaceflight are known to result in skeletal muscle atrophy that leads to diminished functional performance. To assess if inhibition of the growth factor myostatin has potential to reverse these effects, mice were treated with a myostatin antibody while housed...

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Bibliographic Details
Main Authors: Rosamund C Smith, Martin S Cramer, Pamela J Mitchell, Jonathan Lucchesi, Alicia M Ortega, Eric W Livingston, Darryl Ballard, Ling Zhang, Jeff Hanson, Kenneth Barton, Shawn Berens, Kelly M Credille, Ted A Bateman, Virginia L Ferguson, Yanfei L Ma, Louis S Stodieck
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0230818

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