DNA damage protection: an excellent application of bioactive compounds

• Main Authors: Pinderpal Kaur, Sukhvinder Singh Purewal, Kawaljit Singh Sandhu, Maninder Kaur
• Format: Article
• Language: English
• Published: SpringerOpen 2019-01-01
• Series: Bioresources and Bioprocessing
• Subjects: DNA; Agriculture; Chronic disorders; Natural extracts; Breeders
• Online Access: http://link.springer.com/article/10.1186/s40643-019-0237-9

Abstract Discovery of deoxyribonucleic acid (DNA) solved out the mystery of cellular functioning and abnormality in cellular metabolism. Understanding the coding of DNA resulted in enormous medical growth and helps the researchers in finding the genes which trigger major chronic diseases in humans. Further, the structural and sequential analysis brought humans into a new era of medical industry. The advancement in understanding of DNA could be a boon for agricultural sector as it allowed the farmers/breeders to choose better varieties with disease resistant features. In developing nations where the staple foods suffers with micronutrient deficiencies and stress conditions, DNA modifications and repair mechanism could solve out their problems. The role of DNA damaging factors and repair mechanism plays a crucial role in occurrence of certain disorders. Extracts prepared from various natural resources could either stop or slow down the process of DNA damage. This will help to eradicate major disorders related to DNA from human race. Further on the basis of type and dose of natural extracts, it would ease the planning of diets for patients suffering from chronic disorders.