Heterogeneity of exhausted T cells in the tumor microenvironment is linked to patient survival following resection in hepatocellular carcinoma

Heterogeneity of exhausted T cells in the tumor microenvironment is linked to patient survival following resection in hepatocellular carcinoma

Despite the success of monotherapies based on blockade of programmed cell death 1 (PD-1) in human melanoma, most patients do not experience durable clinical benefit. T-cell infiltration and/or the presence of PD-L1 in tumors may be used as indicators of clinical response; However, recent studies rep...

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Bibliographic Details
Main Authors: Fangming Liu, Weiren Liu, David E. Sanin, Guangshuai Jia, Mengxin Tian, Han Wang, Bijun Zhu, Yan Lu, Tiankui Qiao, Xiangdong Wang, Yinghong Shi, Duojiao Wu
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:OncoImmunology
Subjects:
t cell exhaustion
hepatocellular carcinoma
prognosis
microenvironment
Online Access:http://dx.doi.org/10.1080/2162402X.2020.1746573

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